Pepperoni bread freezes very well and can be kept in the freezer for about two months. You can even prepare the bread in advance, bake it and store it in the freezer until you're ready to serve it. When you're ready to put everything on the plate, defrost the bread the night before or a few hours before taking it out. Place it in the oven at a low temperature so that it heats up completely and becomes sticky again with the cheese.
Pepperoni bread is a kind of cousin to pepperoni rolls, which first became popular as a basic lunch for coal miners in West Virginia.